7XME

Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative

7XME の概要

• エントリーDOI: 10.2210/pdb7xme/pdb
• 分子名称: Polymerase basic protein 2, IODIDE ION, (2~{S},3~{S})-3-[[5-dimethoxyphosphoryl-4-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: inhibitor, complex, rna binding protein
• 由来する生物種: Influenza A virus (A/Victoria/3/1975(H3N2))
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 77969.13

構造登録者

Zhang, Z. (登録日: 2022-04-25, 公開日: 2023-05-03, 最終更新日: 2023-11-29)

• 主引用文献: Zhang, Z.,Liu, X.; Discovery of a novel azaindole derivatives targeting the influenza PB2 cap binding region; To Be Published,

実験手法

X-RAY DIFFRACTION (2.521 Å)