7XLV

Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (G7I mutant)

Summary for 7XLV

• Entry DOI: 10.2210/pdb7xlv/pdb
• Descriptor: DNA (5'-D(*CP*AP*CP*CP*TP*AP*IP*CP*GP*A)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL, SILVER ION, ... (4 entities in total)
• Functional Keywords: silver, nanocluster, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 8165.63

Authors

Kondo, J.,Cerretani, C.,Vosch, T. (deposition date: 2022-04-23, release date: 2022-07-13, Last modification date: 2023-11-29)

Primary citation

Cerretani, C.,Liisberg, M.B.,Ruck, V.,Kondo, J.,Vosch, T.
The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster.
Nanoscale Adv, 4:3212-3217, 2022

PubMed Abstract: The effect of replacing guanosines with inosines in the two stabilizing strands (5'-CACCTAGCGA-3') of the NIR emissive DNA-AgNC was investigated. The spectroscopic behavior of the inosine mutants is position-dependent: when the guanosine in position 7 was exchanged, the nanosecond fluorescence decay time shortened, while having the inosine in position 9 made the decay time longer. Thanks to structural information gained from single crystal X-ray diffraction measurements, it was possible to propose a mechanistic origin for the observed changes.

PubMed: 36132821
DOI: 10.1039/d2na00325b

Experimental method

X-RAY DIFFRACTION (1.1 Å)