7XKT

Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution

Summary for 7XKT

• Entry DOI: 10.2210/pdb7xkt/pdb
• EMDB information: 33254 33255 33256 33270
• Descriptor: Gap junction delta-2 protein,Soluble cytochrome b562, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ... (5 entities in total)
• Functional Keywords: connexin 36, cx36, gap junction channel, bril, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 561158.63

Authors

Cho, H.J.,Lee, S.N.,Jeong, H.,Ryu, B.,Lee, H.J.,Woo, J.S.,Lee, H.H. (deposition date: 2022-04-20, release date: 2023-03-22)

• Primary citation: Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Kim, M.,Yoo, J.,Woo, J.S.,Lee, H.H.; Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.; Nat Commun, 14:1347-1347, 2023; PubMed: 36906653; DOI: 10.1038/s41467-023-37040-8

Experimental method

ELECTRON MICROSCOPY (2.2 Å)