7XKI

Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry)

Summary for 7XKI

Entry DOI	10.2210/pdb7xki/pdb
EMDB information	33254
Descriptor	Gap junction delta-2 protein,Soluble cytochrome b562, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE (2 entities in total)
Functional Keywords	connexin 36, gap junction channel, cx36, gjd2, bril, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	503999.88
Authors	Cho, H.J.,Lee, S.N.,Jeong, H.,Ryu, B.,Lee, H.J.,Woo, J.S.,Lee, H.H. (deposition date: 2022-04-19, release date: 2023-03-22)
Primary citation	Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Kim, M.,Yoo, J.,Woo, J.S.,Lee, H.H. Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14:1347-1347, 2023 Cited by PubMed: 36906653 DOI: 10.1038/s41467-023-37040-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation