7XK8
Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25
Summary for 7XK8
Entry DOI | 10.2210/pdb7xk8/pdb |
EMDB information | 33247 |
Descriptor | Neuromedin-U-25, Neuromedin-U receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total) |
Functional Keywords | gpcr, complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 134838.01 |
Authors | Zhao, W.,Wenru, Z.,Mu, W.,Minmin, L.,Shutian, C.,Tingting, T.,Gisela, S.,Holger, W.,Albert, B.,Cuiying, Y.,Xiaojing, C.,Han, S.,Wu, B.,Zhao, Q. (deposition date: 2022-04-19, release date: 2023-02-22) |
Primary citation | Zhao, W.,Zhang, W.,Wang, M.,Lu, M.,Chen, S.,Tang, T.,Schnapp, G.,Wagner, H.,Brennauer, A.,Yi, C.,Chu, X.,Han, S.,Wu, B.,Zhao, Q. Ligand recognition and activation of neuromedin U receptor 2. Nat Commun, 13:7955-7955, 2022 Cited by PubMed: 36575163DOI: 10.1038/s41467-022-34814-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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