7XK2
Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex
Summary for 7XK2
Entry DOI | 10.2210/pdb7xk2/pdb |
EMDB information | 33241 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hydroxycarboxylic acid receptor 2, ... (6 entities in total) |
Functional Keywords | niacin receptor, hydroxycarboxylic acid receptor 2, hca2, gi complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 150700.38 |
Authors | Yang, Y.,Kang, H.J.,Gao, R.G.,Wang, J.J.,Han, G.W.,DiBerto, J.F.,Wu, L.J.,Tong, J.H.,Qu, L.,Wu, Y.R.,Pileski, R.,Li, X.M.,Zhang, X.C.,Zhao, S.W.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.H.,Liu, Z.J. (deposition date: 2022-04-19, release date: 2023-02-22, Last modification date: 2023-12-06) |
Primary citation | Yang, Y.,Kang, H.J.,Gao, R.,Wang, J.,Han, G.W.,DiBerto, J.F.,Wu, L.,Tong, J.,Qu, L.,Wu, Y.,Pileski, R.,Li, X.,Zhang, X.C.,Zhao, S.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.,Liu, Z.J. Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14:1692-1692, 2023 Cited by PubMed: 36973264DOI: 10.1038/s41467-023-37177-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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