7XJ2
Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry
Summary for 7XJ2
Entry DOI | 10.2210/pdb7xj2/pdb |
EMDB information | 33217 |
Descriptor | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide (2 entities in total) |
Functional Keywords | channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 485375.42 |
Authors | |
Primary citation | Fan, J.,Hu, L.,Yue, Z.,Liao, D.,Guo, F.,Ke, H.,Jiang, D.,Yang, Y.,Lei, X. Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19:81-90, 2023 Cited by PubMed: 36302896DOI: 10.1038/s41589-022-01166-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
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