7XJ2

Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, C, A, D)	Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP	polymer	1061	120865.4	4	UniProt (B2KYM6) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) UniProt (by SIFTS) (Q8NET8)	Homo sapiens (human)
2	E, F, G, H (B, C, A, D)	N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide	non-polymer		478.4	4	Chemie (EQK)

Sequence modifications

B, C, A, D: 1 - 791 (UniProt: B2KYM6)

PDB	External Database	Details
Ile 25	Val 25	conflict
Arg 117	Gly 117	conflict
Lys 246	Arg 246	conflict
Gly 247	Glu 247	conflict
Ser 573	Gly 573	conflict
Asn 772	Asp 772	conflict

B, C, A, D: 792 - 1061 (PDB: 7XJ2)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	483461.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1913.8
All*	Total formula weight	485375.4

*Water molecules are not included.