7XH6

Crystal structure of CBP bromodomain liganded with CCS1477

Summary for 7XH6

• Entry DOI: 10.2210/pdb7xh6/pdb
• Descriptor: CREB-binding protein, GLYCEROL, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: histone acetyltransferase, cbp, bromodomain, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 33022.01

Authors

Xu, H.,Xiang, Q.,Wang, C.,Zhang, C.,Luo, G.,Wu, X.,Zhang, Y.,Xu, Y. (deposition date: 2022-04-07, release date: 2022-07-27, Last modification date: 2023-11-29)

• Primary citation: Xu, H.,Luo, G.,Wu, T.,Hu, J.,Wang, C.,Wu, X.,Zhang, Y.,Xu, Y.,Xiang, Q.; Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain; Biochem.Biophys.Res.Commun., 623:17-22, 2022; DOI: 10.1016/j.bbrc.2022.07.021

Experimental method

X-RAY DIFFRACTION (1.75 Å)