7XH6
Crystal structure of CBP bromodomain liganded with CCS1477
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CREB-binding protein | polymer | 133 | 15891.3 | 2 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (human) | |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | A, B | (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one | non-polymer | 534.6 | 2 | Chemie (JHL) | |||
5 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
PDB | External Database | Details |
---|---|---|
Met 1065 | - | expression tag |
Lys 1066 | - | expression tag |
Lys 1067 | - | expression tag |
Gly 1068 | - | expression tag |
His 1069 | - | expression tag |
His 1070 | - | expression tag |
His 1071 | - | expression tag |
His 1072 | - | expression tag |
His 1073 | - | expression tag |
His 1074 | - | expression tag |
Leu 1075 | - | expression tag |
Val 1076 | - | expression tag |
Pro 1077 | - | expression tag |
Arg 1078 | - | expression tag |
Gly 1079 | - | expression tag |
Ser 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31782.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1239.4 | |
All* | Total formula weight | 33022.0 |