7XFR

Crystal structure of WIPI2b in complex with the second site of ATG16L1

Summary for 7XFR

Entry DOI	10.2210/pdb7xfr/pdb
Descriptor	Isoform 2 of WD repeat domain phosphoinositide-interacting protein 2, Autophagy-related protein 16-1 (3 entities in total)
Functional Keywords	wipi2b, atg16l1, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	86252.82
Authors	Gong, X.Y.,Pan, L.F. (deposition date: 2022-04-02, release date: 2023-03-08, Last modification date: 2023-11-29)
Primary citation	Gong, X.,Wang, Y.,Tang, Y.,Wang, Y.,Zhang, M.,Li, M.,Zhang, Y.,Pan, L. ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy. Sci Adv, 9:eadf0824-eadf0824, 2023 Cited by PubMed: 36857448 DOI: 10.1126/sciadv.adf0824 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation