7XB0

Crystal structure of Omicron BA.2 RBD complexed with hACE2

7XB0 の概要

• エントリーDOI: 10.2210/pdb7xb0/pdb
• 分子名称: Angiotensin-converting enzyme 2, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, omicron, rbd, hace2, complex structure, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93242.83

構造登録者

Li, L.,Liao, H.,Meng, Y.,Li, W. (登録日: 2022-03-19, 公開日: 2022-07-06, 最終更新日: 2023-11-29)

• 主引用文献: Li, L.,Liao, H.,Meng, Y.,Li, W.,Han, P.,Liu, K.,Wang, Q.,Li, D.,Zhang, Y.,Wang, L.,Fan, Z.,Zhang, Y.,Wang, Q.,Zhao, X.,Sun, Y.,Huang, N.,Qi, J.,Gao, G.F.; Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.; Cell, 185:2952-2960.e10, 2022; PubMed: 35809570; DOI: 10.1016/j.cell.2022.06.023

実験手法

X-RAY DIFFRACTION (2.9 Å)