7XAV

Structure of somatostatin receptor 2 bound with lanreotide.

7XAV の概要

• エントリーDOI: 10.2210/pdb7xav/pdb
• EMDBエントリー: 33100
• 分子名称: Somatostatin receptor type 2,LargeBit, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• 機能のキーワード: g protein coupled receptor, cryo-em, sst analogues, polypeptide drugs, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 184450.02

構造登録者

Bo, Q.,Yang, F.,Li, Y.G.,Meng, X.Y.,Zhang, H.H.,Zhou, Y.X.,Ling, S.L.,Sun, D.M.,Lv, P.,Liu, L.,Shi, P.,Tian, C.L. (登録日: 2022-03-19, 公開日: 2022-08-31)

• 主引用文献: Bo, Q.,Yang, F.,Li, Y.,Meng, X.,Zhang, H.,Zhou, Y.,Ling, S.,Sun, D.,Lv, P.,Liu, L.,Shi, P.,Tian, C.; Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues.; Cell Discov, 8:47-47, 2022; PubMed: 35595746; DOI: 10.1038/s41421-022-00405-2

実験手法

ELECTRON MICROSCOPY (2.87 Å)