7X9G
Crystal structure of human EDA and EDAR
Summary for 7X9G
Entry DOI | 10.2210/pdb7x9g/pdb |
Descriptor | Ectodysplasin-A, secreted form, Tumor necrosis factor receptor superfamily member EDAR (2 entities in total) |
Functional Keywords | ligand-receptor complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 48586.94 |
Authors | |
Primary citation | Yu, K.,Huang, C.,Wan, F.,Jiang, C.,Chen, J.,Li, X.,Wang, F.,Wu, J.,Lei, M.,Wu, Y. Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants. Nat Commun, 14:767-767, 2023 Cited by PubMed: 36765055DOI: 10.1038/s41467-023-36367-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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