7X91
The SARS-CoV-2 receptor binding domain bound with an Fv-clasp form of a human neutralizing antibody Ab496
Summary for 7X91
Entry DOI | 10.2210/pdb7x91/pdb |
EMDB information | 33063 |
Descriptor | Spike glycoprotein, An Fv-clasp version of the Ab496 heavy chain, An Fv-clasp version of the Ab496 light chain, ... (4 entities in total) |
Functional Keywords | severe acute respiratory syndrome coronavirus-2 (sars-cov-2) spike trimer, covid-19, human neutralizing antibody, rbd, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 3 |
Total formula weight | 186196.33 |
Authors | Kamada, K.,Shirouzu, M. (deposition date: 2022-03-15, release date: 2022-12-07, Last modification date: 2024-10-09) |
Primary citation | Takeshita, M.,Fukuyama, H.,Kamada, K.,Matsumoto, T.,Makino-Okamura, C.,Uchikubo-Kamo, T.,Tomabechi, Y.,Hanada, K.,Moriyama, S.,Takahashi, Y.,Ishigaki, H.,Nakayama, M.,Nguyen, C.T.,Kitagawa, Y.,Itoh, Y.,Imai, M.,Maemura, T.,Furusawa, Y.,Ueki, H.,Iwatsuki-Horimoto, K.,Ito, M.,Yamayoshi, S.,Kawaoka, Y.,Shirouzu, M.,Ishii, M.,Saya, H.,Kondo, Y.,Kaneko, Y.,Suzuki, K.,Fukunaga, K.,Takeuchi, T. Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models. Iscience, 25:105596-105596, 2022 Cited by PubMed: 36406861DOI: 10.1016/j.isci.2022.105596 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
Download full validation report