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7X7N

3D model of the 3-RBD up single trimeric spike protein of SARS-CoV2 in the presence of synthetic peptide SIH-5.

Summary for 7X7N
Entry DOI10.2210/pdb7x7n/pdb
EMDB information33042
DescriptorSpike glycoprotein, Synthetic peptide SIH-5, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordsspike protein, sars-cov2, complex, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
More
Total number of polymer chains9
Total formula weight463757.97
Authors
Khatri, B.,Pramanick, I.,Malladi, S.K.,Rajmani, R.S.,Kumar, S.,Ghosh, P.,Sengupta, N.,Rahisuddin, R.,Kumaran, S.,Ringe, R.P.,Varadarajan, R.,Dutta, S.,Chatterjee, J. (deposition date: 2022-03-10, release date: 2022-04-27, Last modification date: 2022-11-16)
Primary citationKhatri, B.,Pramanick, I.,Malladi, S.K.,Rajmani, R.S.,Kumar, S.,Ghosh, P.,Sengupta, N.,Rahisuddin, R.,Kumar, N.,Kumaran, S.,Ringe, R.P.,Varadarajan, R.,Dutta, S.,Chatterjee, J.
A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein.
Nat.Chem.Biol., 18:1046-1055, 2022
Cited by
PubMed: 35654847
DOI: 10.1038/s41589-022-01060-0
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.47 Å)
Structure validation

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