7X2D
Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-Gs complex
Summary for 7X2D
Entry DOI | 10.2210/pdb7x2d/pdb |
EMDB information | 32965 |
Descriptor | D(1A) dopamine receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | gpcr, dopamine receptor, mini-gs, membrane protein, tavapadon |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 146711.00 |
Authors | |
Primary citation | Teng, X.,Chen, S.,Nie, Y.,Xiao, P.,Yu, X.,Shao, Z.,Zheng, S. Ligand recognition and biased agonism of the D1 dopamine receptor. Nat Commun, 13:3186-3186, 2022 Cited by PubMed: 35676276DOI: 10.1038/s41467-022-30929-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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