7WU8

Crystal structure of Harmonin-homology domain 2 (HHD2) of human RTEL1

Summary for 7WU8

Entry DOI	10.2210/pdb7wu8/pdb
Descriptor	Regulator of telomere elongation helicase 1 (2 entities in total)
Functional Keywords	rtel1, harmonin homology domain 2, protein-protein interaction, protein-dna interaction, protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	7
Total formula weight	74459.15
Authors	Kumar, N.,Rothweiler, U.,Singh, M. (deposition date: 2022-02-07, release date: 2023-08-09, Last modification date: 2024-02-21)
Primary citation	Kumar, N.,Taneja, A.,Ghosh, M.,Rothweiler, U.,Sundaresan, N.R.,Singh, M. Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites. Nucleic Acids Res., 52:1450-1470, 2024 Cited by PubMed: 38153196 DOI: 10.1093/nar/gkad1208 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.599 Å)

Structure validation