7WSZ

human glyoxalase I (with C-ter His tag) in glycerol-bound form

Summary for 7WSZ

• Entry DOI: 10.2210/pdb7wsz/pdb
• Descriptor: Lactoylglutathione lyase, ZINC ION, GLYCEROL, ... (7 entities in total)
• Functional Keywords: glyoxalase i, zinc metalloenzyme, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 44659.78

Authors

Usami, M.,Ando, K.,Yokoyama, H. (deposition date: 2022-02-03, release date: 2022-04-13, Last modification date: 2023-11-29)

• Primary citation: Usami, M.,Ando, K.,Shibuya, A.,Takasawa, R.,Yokoyama, H.; Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference.; Febs Lett., 596:1458-1467, 2022; PubMed: 35363883; DOI: 10.1002/1873-3468.14344

Experimental method

X-RAY DIFFRACTION (1.52 Å)