7WPV
Fab14 - a SARS-CoV2 RBD neutralising antibody
Summary for 7WPV
Entry DOI | 10.2210/pdb7wpv/pdb |
Descriptor | Fab14 light chain, Fab14 heavy chain (3 entities in total) |
Functional Keywords | sars-cov2 rbd neutralising antibody, protein binding, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 48102.32 |
Authors | Lin, J.Q.,El Sahili, A.,Lescar, J. (deposition date: 2022-01-24, release date: 2022-03-30, Last modification date: 2023-11-29) |
Primary citation | Ku, Z.,Xie, X.,Lin, J.,Gao, P.,Wu, B.,El Sahili, A.,Su, H.,Liu, Y.,Ye, X.,Tan, E.Y.,Li, X.,Fan, X.,Goh, B.C.,Xiong, W.,Boyd, H.,Muruato, A.E.,Deng, H.,Xia, H.,Zou, J.,Kalveram, B.K.,Menachery, V.D.,Zhang, N.,Lescar, J.,Shi, P.Y.,An, Z. Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth. Nat Commun, 13:5552-5552, 2022 Cited by PubMed: 36138032DOI: 10.1038/s41467-022-33284-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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