7WHZ

SARS-CoV-2 spike protein in complex with three human neutralizing antibodies

7WHZ の概要

• エントリーDOI: 10.2210/pdb7whz/pdb
• EMDBエントリー: 32516
• 分子名称: Spike protein S1, XMA04 heavy chain variable domain, XMA01 heavy chain variable domain, ... (8 entities in total)
• 機能のキーワード: sars-cov-2, omicron, spike protein, neutralizing antibody, cryo-em, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 96855.36

構造登録者

Zheng, Q.,Li, S.,Sun, H.,Zheng, Z.,Wang, S. (登録日: 2022-01-01, 公開日: 2022-06-22)

• 主引用文献: Wang, S.,Sun, H.,Zhang, Y.,Yuan, L.,Wang, Y.,Zhang, T.,Wang, S.,Zhang, J.,Yu, H.,Xiong, H.,Tang, Z.,Liu, L.,Huang, Y.,Chen, X.,Li, T.,Ying, D.,Liu, C.,Chen, Z.,Yuan, Q.,Zhang, J.,Cheng, T.,Li, S.,Guan, Y.,Zheng, Q.,Zheng, Z.,Xia, N.; Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.; Cell Rep, 39:110862-110862, 2022; PubMed: 35594869; DOI: 10.1016/j.celrep.2022.110862

実験手法

ELECTRON MICROSCOPY (3.42 Å)