7WFC

X-ray structure of HKU1-PLP2(Cys109Ser) catalytic mutant in complex with free ubiquitin

7WFC の概要

• エントリーDOI: 10.2210/pdb7wfc/pdb
• 分子名称: Papain-like protease, 60S ribosomal protein L40, ZINC ION, ... (5 entities in total)
• 機能のキーワード: hku1-plp2-ub complex, hydrolase
• 由来する生物種: Human coronavirus HKU1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43726.57

構造登録者

Xiong, Y.X.,Fu, Z.Y.,Huang, H. (登録日: 2021-12-26, 公開日: 2022-12-28, 最終更新日: 2023-11-29)

• 主引用文献: Xiong, Y.,Huang, B.,Yang, Y.,Fu, X.,Fu, Z.,Xu, H.,Liu, M.,Cao, D.,Zhang, M.,Yang, H.,Niu, X.,Yu, C.,Huang, H.; The substrate selectivity of papain-like proteases from human-infecting coronaviruses correlates with innate immune suppression.; Sci.Signal., 16:eade1985-eade1985, 2023; PubMed: 37130166; DOI: 10.1126/scisignal.ade1985

実験手法

X-RAY DIFFRACTION (2.6 Å)