7WC8
Crystal structure of serotonin 2A receptor in complex with lumateperone
Summary for 7WC8
Entry DOI | 10.2210/pdb7wc8/pdb |
Descriptor | 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, MAGNESIUM ION, CHOLESTEROL, ... (8 entities in total) |
Functional Keywords | serotonin 2a receptor, serotonin, 5-ht, membrane protein, lumateperone |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 48287.01 |
Authors | |
Primary citation | Cao, D.,Yu, J.,Wang, H.,Luo, Z.,Liu, X.,He, L.,Qi, J.,Fan, L.,Tang, L.,Chen, Z.,Li, J.,Cheng, J.,Wang, S. Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375:403-411, 2022 Cited by PubMed: 35084960DOI: 10.1126/science.abl8615 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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