7W8X

DMSPP- and 6-Me-Trp-bound dimethylallyl tryptophan synthase, IptA

Summary for 7W8X

Entry DOI	10.2210/pdb7w8x/pdb
Descriptor	6-dimethylallyltryptophan synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	aromatic prenyltransferase, stpreptomyces, secondary metabolites, transferase
Biological source	Streptomyces sp. SN-593
Total number of polymer chains	1
Total formula weight	40302.87
Authors	Suemune, H.,Nagano, S.,Tomoya, H. (deposition date: 2021-12-08, release date: 2022-10-19, Last modification date: 2023-11-29)
Primary citation	Suemune, H.,Nishimura, D.,Mizutani, K.,Sato, Y.,Hino, T.,Takagi, H.,Shiozaki-Sato, Y.,Takahashi, S.,Nagano, S. Crystal structures of a 6-dimethylallyltryptophan synthase, IptA: Insights into substrate tolerance and enhancement of prenyltransferase activity. Biochem.Biophys.Res.Commun., 593:144-150, 2022 Cited by PubMed: 35074664 DOI: 10.1016/j.bbrc.2022.01.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation