7W7L
Structure of NF-kB p52 homodimer bound to 13-mer A/T-centric P-Selectin kB DNA fragment
Summary for 7W7L
Entry DOI | 10.2210/pdb7w7l/pdb |
Descriptor | Nuclear factor NF-kappa-B p52 subunit, DNA (5'-D(*GP*GP*GP*GP*GP*TP*AP*AP*CP*CP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*GP*TP*TP*AP*CP*CP*CP*CP*C)-3'), ... (4 entities in total) |
Functional Keywords | dna-protein complex, transcription factor, transcription, dna binding protein, dna binding protein-dna complex, dna binding protein-dna-dna complex, dna binding protein-dna/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 81424.81 |
Authors | Meshcheryakov, V.A.,Wang, V.Y.-F. (deposition date: 2021-12-05, release date: 2022-01-26, Last modification date: 2023-11-29) |
Primary citation | Pan, W.,Meshcheryakov, V.A.,Li, T.,Wang, Y.,Ghosh, G.,Wang, V.Y. Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation. Elife, 12:-, 2023 Cited by PubMed: 36779700DOI: 10.7554/eLife.86258 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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