7W7L

Structure of NF-kB p52 homodimer bound to 13-mer A/T-centric P-Selectin kB DNA fragment

Summary for 7W7L

• Entry DOI: 10.2210/pdb7w7l/pdb
• Descriptor: Nuclear factor NF-kappa-B p52 subunit, DNA (5'-D(*GP*GP*GP*GP*GP*TP*AP*AP*CP*CP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*GP*TP*TP*AP*CP*CP*CP*CP*C)-3'), ... (4 entities in total)
• Functional Keywords: dna-protein complex, transcription factor, transcription, dna binding protein, dna binding protein-dna complex, dna binding protein-dna-dna complex, dna binding protein-dna/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 81424.81

Authors

Meshcheryakov, V.A.,Wang, V.Y.-F. (deposition date: 2021-12-05, release date: 2022-01-26, Last modification date: 2023-11-29)

• Primary citation: Pan, W.,Meshcheryakov, V.A.,Li, T.,Wang, Y.,Ghosh, G.,Wang, V.Y.; Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.; Elife, 12:-, 2023; PubMed: 36779700; DOI: 10.7554/eLife.86258

Experimental method

X-RAY DIFFRACTION (3 Å)