7W7B

Heme exporter HrtBA in complex with protoporphyrin IX containing manganese(III), high resolution data

Summary for 7W7B

Entry DOI	10.2210/pdb7w7b/pdb
Descriptor	Putative ABC transport system, ATP-binding protein, Putative ABC transport system integral membrane protein, (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, ... (6 entities in total)
Functional Keywords	heme efflux, heme extraction, heme detoxification, abc transporter, 4-helix tmd, atp-binding protein-membrane protein complex, membrane protein
Biological source	Corynebacterium diphtheriae NCTC 13129 More
Total number of polymer chains	12
Total formula weight	366354.24
Authors	Hisano, T.,Nakamura, H.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y. (deposition date: 2021-12-04, release date: 2022-06-22, Last modification date: 2023-11-29)
Primary citation	Nakamura, H.,Hisano, T.,Rahman, M.M.,Tosha, T.,Shirouzu, M.,Shiro, Y. Structural basis for heme detoxification by an ATP-binding cassette-type efflux pump in gram-positive pathogenic bacteria. Proc.Natl.Acad.Sci.USA, 119:e2123385119-e2123385119, 2022 Cited by PubMed: 35767641 DOI: 10.1073/pnas.2123385119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation