7W6D
Polyketide cyclase OAC-F24I mutant from Cannabis sativa in complex with olivetolic acid
Summary for 7W6D
| Entry DOI | 10.2210/pdb7w6d/pdb |
| Descriptor | Olivetolic acid cyclase, 2,4-bis(oxidanyl)-6-pentyl-benzoic acid (3 entities in total) |
| Functional Keywords | olivetolic acid cyclase, polypeptide cyclase, lyase |
| Biological source | Cannabis sativa (Hemp, Marijuana) |
| Total number of polymer chains | 2 |
| Total formula weight | 24840.50 |
| Authors | Nakashima, Y.,Lee, Y.E.,Morita, H. (deposition date: 2021-12-01, release date: 2022-02-02, Last modification date: 2023-11-29) |
| Primary citation | Lee, Y.E.,Nakashima, Y.,Kodama, T.,Chen, X.,Morita, H. Dual Engineering of Olivetolic Acid Cyclase and Tetraketide Synthase to Generate Longer Alkyl-Chain Olivetolic Acid Analogs. Org.Lett., 24:410-414, 2022 Cited by PubMed: 34939812DOI: 10.1021/acs.orglett.1c04089 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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