7W53
Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 1-Gq protein complex
Summary for 7W53
Entry DOI | 10.2210/pdb7w53/pdb |
EMDB information | 32313 |
Descriptor | Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Neuromedin-U-25, ... (6 entities in total) |
Functional Keywords | cryo-em, gpcr, neuromedin u, neuromedin u receptor 1, gq, complex, signaling protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 203126.89 |
Authors | |
Primary citation | You, C.,Zhang, Y.,Xu, P.,Huang, S.,Yin, W.,Eric Xu, H.,Jiang, Y. Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13:2045-2045, 2022 Cited by PubMed: 35440625DOI: 10.1038/s41467-022-29683-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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