7W4O

The structure of KATP H175K mutant in pre-open state

Summary for 7W4O

• Entry DOI: 10.2210/pdb7w4o/pdb
• EMDB information: 32310
• Descriptor: ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: katp, kir6.2, sur1, nn414, adp, atp, transport protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 888708.22

Authors

Chen, L.,Wang, M. (deposition date: 2021-11-28, release date: 2022-06-01)

• Primary citation: Wang, M.,Wu, J.X.,Ding, D.,Chen, L.; Structural insights into the mechanism of pancreatic K ATP channel regulation by nucleotides.; Nat Commun, 13:2770-2770, 2022; PubMed: 35589716; DOI: 10.1038/s41467-022-30430-4

Experimental method

ELECTRON MICROSCOPY (2.96 Å)