7W1M
Cryo-EM structure of human cohesin-CTCF-DNA complex
Summary for 7W1M
Entry DOI | 10.2210/pdb7w1m/pdb |
EMDB information | 32252 |
Descriptor | Structural maintenance of chromosomes protein 1A, BERYLLIUM TRIFLUORIDE ION, ZINC ION, ... (11 entities in total) |
Functional Keywords | cohesin, nipbl, ctcf, dna, chromosome folding, topologically associating domain, chromatin loops, dna loop extrusion, sister chromatid cohesion, complex, atpase, heat repeat protein, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 826702.61 |
Authors | |
Primary citation | Zhang, H.,Shi, Z.,Banigan, E.J.,Kim, Y.,Yu, H.,Bai, X.C.,Finkelstein, I.J. CTCF and R-loops are boundaries of cohesin-mediated DNA looping. Mol.Cell, 83:2856-2871.e8, 2023 Cited by PubMed: 37536339DOI: 10.1016/j.molcel.2023.07.006 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.5 Å) |
Structure validation
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