7VYQ
Short chain dehydrogenase (SCR) cryoEM structure with NADP and ethyl 4-chloroacetoacetate
Summary for 7VYQ
Entry DOI | 10.2210/pdb7vyq/pdb |
EMDB information | 32211 |
Descriptor | Carbonyl Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 4-chloranyl-3-oxidanylidene-butanoate (3 entities in total) |
Functional Keywords | rossman fold, tetramer, tag-free, wild type with nadph, oxidoreductase |
Biological source | Candida parapsilosis (Yeast) |
Total number of polymer chains | 4 |
Total formula weight | 124451.46 |
Authors | Li, Y.H.,Zhang, R.Z.,Wang, C.,Forouhar, F.,Clarke, O.,Vorobiev, S.,Singh, S.,Montelione, G.T.,Szyperski, T.,Xu, Y.,Hunt, J.F. (deposition date: 2021-11-15, release date: 2022-04-06, Last modification date: 2024-06-26) |
Primary citation | Li, Y.,Zhang, R.,Wang, C.,Forouhar, F.,Clarke, O.B.,Vorobiev, S.,Singh, S.,Montelione, G.T.,Szyperski, T.,Xu, Y.,Hunt, J.F. Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. Embo J., 41:e108368-e108368, 2022 Cited by PubMed: 35801308DOI: 10.15252/embj.2021108368 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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