7VTG

Pseudouridine bound structure of Pseudouridine kinase (PUKI) S30A mutant from Escherichia coli strain B

Summary for 7VTG

Entry DOI	10.2210/pdb7vtg/pdb
Descriptor	Pseudouridine kinase, 5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione (3 entities in total)
Functional Keywords	pseudouridine kinase, pseudourdine, transferase, pfkb family
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	136037.18
Authors	Kim, S.H.,Rhee, S. (deposition date: 2021-10-29, release date: 2022-04-06, Last modification date: 2023-11-29)
Primary citation	Kim, S.H.,Kim, M.,Park, D.,Byun, S.,Rhee, S. Substrate-binding loop interactions with pseudouridine trigger conformational changes that promote catalytic efficiency of pseudouridine kinase PUKI. J.Biol.Chem., 298:101869-101869, 2022 Cited by PubMed: 35346685 DOI: 10.1016/j.jbc.2022.101869 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89859128388 Å)

Structure validation