7VSG

Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in PtdSer-occluded E2-Pi state.

7VSG の概要

• エントリーDOI: 10.2210/pdb7vsg/pdb
• EMDBエントリー: 32110
• 分子名称: Phospholipid-transporting ATPase IG, Cell cycle control protein 50A, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: flippase, p4-atpase, membrane protein, phospholipid transporter, transport protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 167013.14

構造登録者

Nakanishii, H.,Abe, K. (登録日: 2021-10-26, 公開日: 2021-12-29, 最終更新日: 2022-02-16)

• 主引用文献: Nakanishi, H.,Hayashida, K.,Nishizawa, T.,Oshima, A.,Abe, K.; Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2.; J.Biol.Chem., 298:101498-101498, 2022; PubMed: 34922944; DOI: 10.1016/j.jbc.2021.101498

実験手法

ELECTRON MICROSCOPY (3.9 Å)