7VQP
Vitamin D receptor complexed with a lithocholic acid derivative
Summary for 7VQP
| Entry DOI | 10.2210/pdb7vqp/pdb |
| Descriptor | Vitamin D3 receptor, Mediator of RNA polymerase II transcription subunit 1, 3-((R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-(2-hydroxy-2-methylpropyl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)propanoic acid, ... (4 entities in total) |
| Functional Keywords | vitamin d receptor, lithocholic acid, transcription |
| Biological source | Rattus norvegicus More |
| Total number of polymer chains | 2 |
| Total formula weight | 32669.69 |
| Authors | Kato, K.,Numoto, N.,Kagechika, H.,Tanatani, A.,Ito, N. (deposition date: 2021-10-20, release date: 2022-03-09, Last modification date: 2023-11-29) |
| Primary citation | Yoshihara, A.,Kawasaki, H.,Masuno, H.,Takada, K.,Numoto, N.,Ito, N.,Hirata, N.,Kanda, Y.,Ishizawa, M.,Makishima, M.,Kagechika, H.,Tanatani, A. Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists. Biomolecules, 12:-, 2022 Cited by PubMed: 35053278DOI: 10.3390/biom12010130 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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