7VOX
The crystal structure of human forkhead box protein A in complex with DNA 2
Summary for 7VOX
Entry DOI | 10.2210/pdb7vox/pdb |
Descriptor | DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3'), Hepatocyte nuclear factor 3-alpha, ... (5 entities in total) |
Functional Keywords | dna-protein complex, transcription factor, transcription, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 67327.97 |
Authors | Choi, Y.,Yoon, H.J.,Lee, H.H. (deposition date: 2021-10-15, release date: 2022-08-17, Last modification date: 2023-11-29) |
Primary citation | Choi, Y.,Luo, Y.,Lee, S.,Jin, H.,Yoon, H.J.,Hahn, Y.,Bae, J.,Lee, H.H. FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations. Nucleic Acids Res., 50:8929-8946, 2022 Cited by PubMed: 35920317DOI: 10.1093/nar/gkac673 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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