7VIJ
Crystal structure of USP7-HUBL domain
Summary for 7VIJ
Entry DOI | 10.2210/pdb7vij/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total) |
Functional Keywords | protein degradation, ubiquitin-specific protease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 61800.25 |
Authors | Feng, N.,Zeng, K.W. (deposition date: 2021-09-27, release date: 2022-08-24, Last modification date: 2023-11-29) |
Primary citation | Zhang, X.W.,Feng, N.,Liu, Y.C.,Guo, Q.,Wang, J.K.,Bai, Y.Z.,Ye, X.M.,Yang, Z.,Yang, H.,Liu, Y.,Yang, M.M.,Wang, Y.H.,Shi, X.M.,Liu, D.,Tu, P.F.,Zeng, K.W. Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy. Sci Adv, 8:eabo0789-eabo0789, 2022 Cited by PubMed: 35947662DOI: 10.1126/sciadv.abo0789 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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