7VI4
Electron crystallographic structure of TIA-1 prion-like domain, A381T mutant
Summary for 7VI4
| Entry DOI | 10.2210/pdb7vi4/pdb |
| Descriptor | TIA-1 prion-like domain (2 entities in total) |
| Functional Keywords | als, prion, fibril, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 1174.24 |
| Authors | Takaba, K.,Maki-Yonekura, S.,Sekiyama, N.,Imamura, K.,Kodama, T.,Tochio, H.,Yonekura, K. (deposition date: 2021-09-24, release date: 2022-09-28) |
| Primary citation | Sekiyama, N.,Takaba, K.,Maki-Yonekura, S.,Akagi, K.I.,Ohtani, Y.,Imamura, K.,Terakawa, T.,Yamashita, K.,Inaoka, D.,Yonekura, K.,Kodama, T.S.,Tochio, H. ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. Proc.Natl.Acad.Sci.USA, 119:e2122523119-e2122523119, 2022 Cited by PubMed: 36112647DOI: 10.1073/pnas.2122523119 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (0.95 Å) |
Structure validation
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