7VGE

Structure of the PDZ deleted variant of HtrA2 protease (S306A)

Summary for 7VGE

Entry DOI	10.2210/pdb7vge/pdb
Descriptor	Serine protease HTRA2, mitochondrial (3 entities in total)
Functional Keywords	serine protease, htra, pdz, hydrolase, oligomer
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	129524.83
Authors	Parui, A.L.,Mishra, V.,Bhaumik, P.,Bose, K. (deposition date: 2021-09-15, release date: 2022-06-01, Last modification date: 2023-11-29)
Primary citation	Parui, A.L.,Mishra, V.,Dutta, S.,Bhaumik, P.,Bose, K. Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2. Structure, 30:1307-1320.e5, 2022 Cited by PubMed: 35738282 DOI: 10.1016/j.str.2022.06.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation