7VGE
Structure of the PDZ deleted variant of HtrA2 protease (S306A)
Summary for 7VGE
Entry DOI | 10.2210/pdb7vge/pdb |
Descriptor | Serine protease HTRA2, mitochondrial (3 entities in total) |
Functional Keywords | serine protease, htra, pdz, hydrolase, oligomer |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 129524.83 |
Authors | Parui, A.L.,Mishra, V.,Bhaumik, P.,Bose, K. (deposition date: 2021-09-15, release date: 2022-06-01, Last modification date: 2023-11-29) |
Primary citation | Parui, A.L.,Mishra, V.,Dutta, S.,Bhaumik, P.,Bose, K. Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2. Structure, 30:1307-1320.e5, 2022 Cited by PubMed: 35738282DOI: 10.1016/j.str.2022.06.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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