7VCE

Structural studies of human inositol monophosphatase-1 inhibition by ebselen

Summary for 7VCE

• Entry DOI: 10.2210/pdb7vce/pdb
• Descriptor: Inositol monophosphatase 1 (2 entities in total)
• Functional Keywords: impase1, ebselen, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 59804.84

Authors

Abuhammad, A.,Laurieri, N.,Rice, A.,Lowe, E.D.,McDonough, M.A.,Singh, N.,Churchill, G.C. (deposition date: 2021-09-02, release date: 2022-09-07, Last modification date: 2023-11-29)

• Primary citation: Abuhammad, A.,Laurieri, N.,Rice, A.,Lowe, E.D.,Singh, N.,Naser, S.M.,Ratrout, S.S.,Churchill, G.C.; Structural and biochemical analysis of human inositol monophosphatase-1 inhibition by ebselen.; J.Biomol.Struct.Dyn., :1-13, 2023; PubMed: 36762717; DOI: 10.1080/07391102.2023.2176925

Experimental method

X-RAY DIFFRACTION (2.6 Å)