7V9D

Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine

7V9D の概要

• エントリーDOI: 10.2210/pdb7v9d/pdb
• 分子名称: Proline--tRNA ligase, ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide, (2S)-azetidine-2-carboxylic acid, ... (7 entities in total)
• 機能のキーワード: protein translation, inhibitor, prs, atp pocket, double drug, ligase
• 由来する生物種: Plasmodium falciparum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 58612.10

構造登録者

Manickam, Y.,Malhotra, N.,Sharma, A. (登録日: 2021-08-24, 公開日: 2022-09-07, 最終更新日: 2023-11-29)

• 主引用文献: Manickam, Y.,Malhotra, N.,Sharma, A.; Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine; To Be Published,

実験手法

X-RAY DIFFRACTION (1.937 Å)