7V7W

Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex with oleoylethanolamide (OEA)

Summary for 7V7W

• Entry DOI: 10.2210/pdb7v7w/pdb
• Descriptor: Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 3-alpha, (Z)-N-(2-hydroxyethyl)octadec-9-enamide, ... (4 entities in total)
• Functional Keywords: hypoxia-inducible factor, transcription
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 81709.87

Authors

Diao, X.,Ren, X.,Li, F.W.,Zhang, M.,Sun, X.,Wu, D. (deposition date: 2021-08-21, release date: 2022-05-18, Last modification date: 2023-11-29)

• Primary citation: Diao, X.,Ye, F.,Zhang, M.,Ren, X.,Tian, X.,Lu, J.,Sun, X.,Hou, Z.,Chen, X.,Li, F.,Zhuang, J.,Ding, H.,Peng, C.,Rastinejad, F.,Luo, C.,Wu, D.; Identification of oleoylethanolamide as an endogenous ligand for HIF-3 alpha.; Nat Commun, 13:2529-2529, 2022; PubMed: 35534502; DOI: 10.1038/s41467-022-30338-z

Experimental method

X-RAY DIFFRACTION (2.507 Å)