7UY4

Aminoglycoside-modifying enzyme ANT-3,9 in complex with spectinomycin and AMP-PNP

Summary for 7UY4

• Entry DOI: 10.2210/pdb7uy4/pdb
• Descriptor: Aminoglycoside (3'') (9) adenylyltransferase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SPECTINOMYCIN, ... (5 entities in total)
• Functional Keywords: antibiotic resistance, drug modifying enzymes, aminoglycoside, spectinonmycin, streptomycin, ames, antimicrobial protein, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 59243.13

Authors

Reeve, S.M.,Lee, R.E.,Das, N.,Jayaraman, S. (deposition date: 2022-05-06, release date: 2023-05-10, Last modification date: 2023-10-25)

• Primary citation: Das, N.,Reeve, S.M.,Lee, R.E.; Characterization of the spectinomycin deactivating enzyme ANT-3,9; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)