7UWT

Structure of Oxygen-Insensitive NAD(P)H-dependent Nitroreductase NfsB_Vv F70A/F108Y (NTR 2.0) in complex with FMN at 1.85 Angstroms resolution

7UWT の概要

• エントリーDOI: 10.2210/pdb7uwt/pdb
• 分子名称: Dihydropteridine reductase, FLAVIN MONONUCLEOTIDE, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: nitroreductase, oxidoreductase, flavoenzyme, metronidazole reductase
• 由来する生物種: Vibrio vulnificus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51317.88

構造登録者

Sharrock, A.V.,Arcus, V.,Mumm, J.S.,Ackerley, D.F. (登録日: 2022-05-03, 公開日: 2022-05-18, 最終更新日: 2023-10-25)

• 主引用文献: Sharrock, A.V.,Mumm, J.S.,Bagdziunas, G.,Cenas, N.,Arcus, V.L.,Ackerley, D.F.; The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Substitutions on Substrate Specificity.; Int J Mol Sci, 24:-, 2023; PubMed: 37047605; DOI: 10.3390/ijms24076633

実験手法

X-RAY DIFFRACTION (1.85 Å)