7UT0
Human DDAH-1, apo form
Summary for 7UT0
Entry DOI | 10.2210/pdb7ut0/pdb |
Related | 7USZ |
Descriptor | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | cardiovascular enzyme, proton pump inhibitors, esomeprazole, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 62443.58 |
Authors | Smith, C.A.,Ghebre, Y.T. (deposition date: 2022-04-26, release date: 2022-05-18, Last modification date: 2023-10-18) |
Primary citation | Smith, C.A.,Ebrahimpour, A.,Novikova, L.,Farina, D.,Bailey, A.O.,Russell, W.K.,Jain, A.,Saltzman, A.B.,Malovannaya, A.,Prasad, B.V.V.,Hu, L.,Ghebre, Y.T. Esomeprazole covalently interacts with the cardiovascular enzyme dimethylarginine dimethylaminohydrolase: Insights into the cardiovascular risk of proton pump inhibitors. Biochim Biophys Acta Gen Subj, 1866:130149-130149, 2022 Cited by PubMed: 35472493DOI: 10.1016/j.bbagen.2022.130149 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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