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7USQ

Crystal Structure of Caspase-3 with Peptide Inhibitor AcDVPD-CHO

Summary for 7USQ
Entry DOI10.2210/pdb7usq/pdb
DescriptorCaspase-3 subunit p17, Caspase-3 subunit p12, Peptide Inhibitor AcDVPD-CHO, ... (4 entities in total)
Functional Keywordscovalent inhibitor, peptide inhibitor, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Total number of polymer chains6
Total formula weight58041.96
Authors
Fuller, J.L.,Finzel, B.C. (deposition date: 2022-04-25, release date: 2022-06-01, Last modification date: 2024-01-17)
Primary citationBresinsky, M.,Strasser, J.M.,Hubmann, A.,Vallaster, B.,McCue, W.M.,Fuller, J.,Singh, G.,Nelson, K.M.,Cuellar, M.E.,Finzel, B.C.,Ashe, K.H.,Walters, M.A.,Pockes, S.
Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
Arch Pharm, 355:e2200095-e2200095, 2022
Cited by
PubMed: 35642311
DOI: 10.1002/ardp.202200095
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.71 Å)
Structure validation

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