7USO
Crystal Structure of Caspase-3 with Peptide Inhibitor AcITVKD-CHO
Summary for 7USO
Entry DOI | 10.2210/pdb7uso/pdb |
Descriptor | Caspase-3 subunit p17, Caspase-3 subunit p12, Peptide Inhibitor AcITVKD-CHO, ... (4 entities in total) |
Functional Keywords | complex, peptide inhibitor, covalent inhibitor, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 58304.44 |
Authors | Fuller, J.L.,Finzel, B.C. (deposition date: 2022-04-25, release date: 2022-06-01, Last modification date: 2023-10-18) |
Primary citation | Bresinsky, M.,Strasser, J.M.,Hubmann, A.,Vallaster, B.,McCue, W.M.,Fuller, J.,Singh, G.,Nelson, K.M.,Cuellar, M.E.,Finzel, B.C.,Ashe, K.H.,Walters, M.A.,Pockes, S. Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis. Arch Pharm, 355:e2200095-e2200095, 2022 Cited by PubMed: 35642311DOI: 10.1002/ardp.202200095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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