7UO7
SARS-CoV-2 replication-transcription complex bound to ATP, in a pre-catalytic state
Summary for 7UO7
Entry DOI | 10.2210/pdb7uo7/pdb |
Related | 7UO4 |
EMDB information | 26641 |
Descriptor | RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (8 entities in total) |
Functional Keywords | rna-directed 5'-3' rna polymerase activity, positive stranded viral rna replication, replication |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 6 |
Total formula weight | 190298.52 |
Authors | Malone, B.F.,Perry, J.K.,Appleby, T.C.,Feng, J.Y.,Campbell, E.A.,Darst, S.A. (deposition date: 2022-04-12, release date: 2022-11-30, Last modification date: 2024-06-12) |
Primary citation | Malone, B.F.,Perry, J.K.,Olinares, P.D.B.,Lee, H.W.,Chen, J.,Appleby, T.C.,Feng, J.Y.,Bilello, J.P.,Ng, H.,Sotiris, J.,Ebrahim, M.,Chua, E.Y.D.,Mendez, J.H.,Eng, E.T.,Landick, R.,Gotte, M.,Chait, B.T.,Campbell, E.A.,Darst, S.A. Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614:781-787, 2023 Cited by PubMed: 36725929DOI: 10.1038/s41586-022-05664-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.09 Å) |
Structure validation
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