7UNY

Crystal structure of D2 nanobody in complex with PfCSS

7UNY の概要

• エントリーDOI: 10.2210/pdb7uny/pdb
• 分子名称: Cysteine-rich small secreted protein CSS, D2 Nanobody, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: 6-cys protein, nanobody, cell invasion
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 99824.54

構造登録者

Scally, S.W.,Lim, P.S.,Cowman, A.F. (登録日: 2022-04-12, 公開日: 2022-11-23, 最終更新日: 2023-10-25)

• 主引用文献: Scally, S.W.,Triglia, T.,Evelyn, C.,Seager, B.A.,Pasternak, M.,Lim, P.S.,Healer, J.,Geoghegan, N.D.,Adair, A.,Tham, W.H.,Dagley, L.F.,Rogers, K.L.,Cowman, A.F.; PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum.; Nat Microbiol, 7:2039-2053, 2022; PubMed: 36396942; DOI: 10.1038/s41564-022-01261-2

実験手法

X-RAY DIFFRACTION (4.13 Å)