7UJ9

Room-temperature X-ray structure of monomeric SARS-CoV-2 main protease catalytic domain (MPro1-199)

Summary for 7UJ9

Entry DOI	10.2210/pdb7uj9/pdb
Descriptor	3C-like proteinase nsp5 (2 entities in total)
Functional Keywords	cysteine protease, catalytic domain, viral enzyme, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	2
Total formula weight	45956.27
Authors	Kovalevsky, A.,Kneller, D.W.,Coates, L. (deposition date: 2022-03-30, release date: 2022-10-05, Last modification date: 2023-10-18)
Primary citation	Nashed, N.T.,Kneller, D.W.,Coates, L.,Ghirlando, R.,Aniana, A.,Kovalevsky, A.,Louis, J.M. Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain. Commun Biol, 5:976-976, 2022 Cited by PubMed: 36114420 DOI: 10.1038/s42003-022-03910-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation