7UJ3
Crystal structure of Human respiratory syncytial virus F variant (construct pXCS847A)
Summary for 7UJ3
Entry DOI | 10.2210/pdb7uj3/pdb |
Descriptor | RSV variant (construct pXCS847A) F2, RSV variant (construct pXCS847A) F1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | rsv, rsvf, pre-fusion, virus |
Biological source | Respiratory syncytial virus More |
Total number of polymer chains | 2 |
Total formula weight | 57644.74 |
Authors | Han, S.,Ammirati, M. (deposition date: 2022-03-30, release date: 2023-04-19, Last modification date: 2023-10-25) |
Primary citation | Che, Y.,Gribenko, A.V.,Song, X.,Handke, L.D.,Efferen, K.S.,Tompkins, K.,Kodali, S.,Nunez, L.,Prasad, A.K.,Phelan, L.M.,Ammirati, M.,Yu, X.,Lees, J.A.,Chen, W.,Martinez, L.,Roopchand, V.,Han, S.,Qiu, X.,DeVincenzo, J.P.,Jansen, K.U.,Dormitzer, P.R.,Swanson, K.A. Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine. Sci Transl Med, 15:eade6422-eade6422, 2023 Cited by PubMed: 37023209DOI: 10.1126/scitranslmed.ade6422 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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